Research and Training in Complementary and Integrative Health

A federal assistance program listed on Grants.gov by National Institutes of Health (Department of Health and Human Services). The listing number stays the same from one funding round to the next, so this page is the one to watch between announcements.

Funding history

Open opportunities under this listing

• HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
  Open PAR-27-045 · closes October 30, 2026
• NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
  Open PAR-25-269 · closes November 13, 2026
• NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
  Open PAR-25-270 · closes November 13, 2026
• NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
  Open PAR-25-271 · closes November 13, 2026
• NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
  Open PAR-25-267 · closes November 17, 2026
• Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
  Open PAR-25-268 · closes November 17, 2026
• Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
  Open PAR-25-274 · closes November 17, 2026
• HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
  Open RFA-AT-25-003 · closes November 23, 2026
• Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)
  Open PA-23-317 · closes November 24, 2026
• NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)
  Open RFA-OD-24-011 · closes December 4, 2026
• Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
  Open PAR-25-378 · closes January 7, 2027
• HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
  Open RFA-NS-25-023 · closes January 15, 2027
• HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
  Open RFA-DA-28-011 · closes January 26, 2027
• HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)
  Open RFA-DA-28-012 · closes January 26, 2027
• Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)
  Open PAR-24-268 · closes January 27, 2027
• BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
  Open RFA-NS-24-031 · closes January 28, 2027
• BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
  Open RFA-MH-26-170 · closes February 8, 2027
• BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)
  Open RFA-DC-27-004 · closes February 11, 2027
• NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
  Open PA-27-100 · closes April 5, 2027
• NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
  Open PA-27-102 · closes April 5, 2027
• Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
  Open RFA-OD-25-003 · closes April 9, 2027
• Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)
  Open PA-24-175 · closes May 7, 2027
• Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
  Open PA-24-176 · closes May 7, 2027
• Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
  Open PA-24-185 · closes May 7, 2027
• Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)
  Open PA-24-187 · closes May 7, 2027
• Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)
  Open PA-24-188 · closes May 7, 2027
• NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)
  Open PA-24-193 · closes May 7, 2027
• NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
  Open PA-24-194 · closes May 7, 2027
• Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)
  Open PA-24-181 · closes May 8, 2027
• Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
  Open PA-24-182 · closes May 8, 2027
• Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)
  Open PA-24-184 · closes May 8, 2027
• Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
  Open PAR-25-210 · closes June 2, 2027
• Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
  Open PAR-25-211 · closes June 2, 2027
• BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
  Open RFA-MH-26-120 · closes June 15, 2027
• BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
  Open RFA-MH-26-140 · closes June 15, 2027
• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
  Open PA-24-254 · closes July 12, 2027
• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
  Open PA-24-253 · closes July 17, 2027
• Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
  Open PAR-24-293 · closes August 18, 2027
• NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
  Open PA-25-080 · closes September 7, 2027
• BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)
  Open RFA-NS-27-015 · closes October 4, 2027
• BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)
  Open RFA-DA-27-004 · closes November 8, 2027
• NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
  Open PA-25-301 · closes January 7, 2028
• NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
  Open PA-25-304 · closes January 7, 2028
• NIH Research Project Grant (Parent R01 Clinical Trial Required)
  Open PA-25-305 · closes January 7, 2028
• NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
  Open PA-25-306 · closes January 7, 2028
• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
  Open PAR-25-134 · closes January 7, 2028
• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
  Open PAR-25-143 · closes January 7, 2028
• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
  Open PAR-25-144 · closes January 7, 2028
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
  Open PAR-25-298 · closes January 7, 2028
• Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)
  Open PAR-25-383 · closes January 28, 2028
• Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)
  Open PA-25-168 · closes May 4, 2028
• Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)
  Open PA-25-280 · closes May 7, 2028
• Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
  Open PA-25-422 · closes May 7, 2028
• Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
  Open PA-25-423 · closes May 7, 2028
• Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
  Open PA-25-425 · closes May 7, 2028
• Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
  Open PA-25-426 · closes May 7, 2028
• Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)
  Open PAR-25-449 · closes June 7, 2028
• BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)
  Open RFA-NS-27-002 · closes June 23, 2028
• Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)
  Open PAR-27-076 · closes July 7, 2028
• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
  Open PAR-25-322 · closes August 25, 2028
• Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
  Open PA-26-001 · closes November 30, 2028
• BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)
  Open RFA-NS-28-010 · closes February 8, 2029
• HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)
  Open RFA-DA-27-016 · closes February 9, 2029
• HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
  Open RFA-NS-27-007 · closes February 20, 2029
• Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)
  Open PA-27-037 · closes April 8, 2029
• NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)
  Open PAR-27-077 · closes May 25, 2029
• Assessing the Feasibility of Incorporating Mechanisms in Multi-site Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R33 Clinical Trial Required)
  Open PAR-28-091 · closes November 16, 2029

Forecasted

• Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
  Forecasted PAR-27-040
• Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)
  Forecasted PAR-27-039
• NIH Pragmatic Trials Conducted in Health Care Systems
  Forecasted PAR-28-010
• Establishing a Research Network to Guide Foundational Research on Human Consciousness
  Forecasted RFA-AT-27-002
• Feasibility Studies to Inform the Design of Future Clinical Trials
  Forecasted PAR-28-011
• Interdisciplinary Research Networks to Advance Biomedical Research on Resilience and Health Optimization
  Forecasted RFA-AT-26-001
• Small Business Translator: MedTech and Digital Health Technologies
  Forecasted FOR-NS-25-017

Recently closed

• BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
  Closed RFA-NS-25-022 · closed September 28, 2026
• BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)
  Closed RFA-NS-25-021 · closed September 28, 2026
• Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
  Closed PAR-25-051 · closed August 18, 2026
• Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
  Closed PAR-23-166 · closed August 7, 2026
• HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
  Closed PAR-25-154 · closed July 16, 2026
• Natural Product Multi-Site Clinical Trial Data Coordinating Center (Collaborative U24 Clinical Trial Required)
  Closed PAR-24-313 · closed July 14, 2026
• Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
  Closed PAR-24-312 · closed July 14, 2026
• Data Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative U24 Clinical Trial Required)
  Closed PAR-24-276 · closed July 14, 2026
• Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative UG3/UH3 Clinical Trial Required)
  Closed PAR-24-275 · closed July 14, 2026
• BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
  Archived RFA-MH-25-105 · closed July 1, 2026
• BRAIN Initiative: Data Archives for the BRAIN Initiative (R24 Clinical Trial Optional)
  Archived RFA-MH-25-110 · closed June 24, 2026
• BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 - Clinical Trials Not Allowed)
  Archived RFA-NS-25-016 · closed June 17, 2026
• BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
  Archived RFA-NS-25-018 · closed June 16, 2026
• BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
  Archived RFA-NS-25-017 · closed June 16, 2026
• BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
  Archived RFA-EY-25-001 · closed June 15, 2026
• NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required)
  Archived PA-25-307 · closed May 24, 2026
• NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
  Archived PA-25-303 · closed May 24, 2026
• NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required)
  Archived PA-24-195 · closed May 24, 2026
• Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - Independent Basic Experimental Studies with Humans Required)
  Archived PA-24-189 · closed May 24, 2026
• Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required)
  Archived PA-24-186 · closed May 24, 2026
• Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required)
  Archived PA-24-183 · closed May 24, 2026
• Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required)
  Archived PA-24-177 · closed May 24, 2026
• Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
  Archived PAR-24-123 · closed February 23, 2026
• Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)
  Archived PAR-23-237 · closed January 25, 2026
• Early-stage Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)
  Archived PAR-23-236 · closed January 25, 2026
• NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Patient-Oriented Research Career Development award (K23 - Clinical Trial Required)
  Archived PAR-24-220 · closed January 22, 2026
• NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Clinical Trials Not Allowed)
  Archived PAR-24-219 · closed January 22, 2026
• NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Basic Experimental Studies with Humans (BESH) Required)
  Archived PAR-24-218 · closed January 22, 2026
• NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Clinical Trials Required)
  Archived PAR-24-217 · closed January 22, 2026
• Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
  Archived PAR-24-294 · closed November 17, 2025
• Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Required)
  Archived PAR-24-134 · closed November 17, 2025
• Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed)
  Archived PAR-24-133 · closed November 17, 2025
• Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Required)
  Archived PAR-24-132 · closed November 17, 2025
• Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed)
  Archived PAR-24-131 · closed November 17, 2025
• Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
  Archived PAR-24-063 · closed November 17, 2025
• HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K23 - Clinical Trial Required)
  Archived PAS-22-207 · closed November 12, 2025
• NIH Blueprint for Neuroscience: Coordination Center for Interoception Research (BPCCIR) (U24, Clinical Trial Not Allowed)
  Archived RFA-AT-25-004 · closed November 10, 2025
• HEAL Commercialization Readiness Pilot (CRP) Program: Embedded Entrepreneurs for Small Businesses in Pain Management (SB1 Clinical Trial Not Allowed)
  Archived PAR-23-069 · closed September 5, 2025
• PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
  Archived PA-24-248 · closed September 5, 2025
• PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
  Archived PA-24-247 · closed September 5, 2025