NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
- Posted
- December 18, 2024
- Closed
- May 24, 2026
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.865, 93.233, 93.838, 93.840, 93.279, 93.839, 93.273, 93.361, 93.853, 93.307, 93.113, 93.173, 93.399, 93.847, 93.866, 93.242, 93.867, 93.121, 93.213, 93.837
- Archives
- June 23, 2026
Program funding history
Awards made under Assistance Listing 93.865 (one of 20 on this opportunity) across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1.3B
- FY2026 obligated
- $1.3B
- FY2027 (to date) obligated
- $0
- Awards in window
- 5,669
Top recipients: Regents of the University of Michigan, University of Washington, The Johns Hopkins University, Regents of the University of California, San Francisco, the, The Leland Stanford Junior University
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s).This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional NOFO.The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
Who can apply
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Small businesses
- For profit organizations other than small businesses
- Native American tribal governments (Federally recognized)
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Independent school districts
- Special district governments
- County governments
- Public housing authorities/Indian housing authorities
- State governments
- City or township governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
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