Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
Federal funding opportunity PAR-25-268 from National Institutes of Health (Department of Health and Human Services).
Apply on Grants.gov →Application closes November 17, 2026
- Posted
- November 21, 2024
- Closes
- November 17, 2026
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.213
- Category
- Health
- Archives
- December 23, 2026
Program funding history
Awards made under Assistance Listing 93.213 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $118.3M
- FY2025 obligated
- $115.4M
- FY2026 (to date) obligated
- $38.7M
- Awards in window
- 683
Top recipients: University of California, San Diego, Yale Univ, The General Hospital Corporation, Regents of the University of California, San Francisco, the, The Spaulding Rehabilitation Hospital Corporation
Source: USAspending.gov · refreshed July 2026
Synopsis
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, along with evidence that the intervention has promise of clinical benefit. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO.
Who can apply
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Private institutions of higher education
- County governments
- Special district governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Public and State controlled institutions of higher education
- Small businesses
- City or township governments
- State governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- For profit organizations other than small businesses
- Independent school districts
- Native American tribal organizations (other than Federally recognized tribal governments)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source.
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