Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)
Federal funding opportunity PAR-27-039 from National Institutes of Health.
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- May 27, 2026
- Closes
- See announcement
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.879, 93.361, 93.840, 93.121, 93.350, 93.846, 93.113, 93.213, 93.837, 93.838, 93.859, 93.233, 93.279, 93.866, 93.173, 93.273, 93.839, 93.143, 93.172, 93.847, 93.865, 93.867
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.879 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $69.5M
- FY2025 obligated
- $78.9M
- FY2026 (to date) obligated
- $25.8M
- Awards in window
- 400
Top recipients: The Leland Stanford Junior University, Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, Trustees of the University of Pennsylvania, the, University of Utah
Source: USAspending.gov · refreshed July 2026
Synopsis
The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. Through this NOFO, NIH and CDC will support early-career scientists as they transition into entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.
Who can apply
- Small businesses
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source.
Get grants like this every Tuesday — free
One email a week: the biggest new federal grants and what’s closing soon. Unsubscribe in one click.
Similar grants
- Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
- Data Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative U24 Clinical Trial Required)
- Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
- Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
- Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
- Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
Never miss a funding deadline again
Grants Radar sends AI-enriched alerts on federal grants and contracts matched to what you do. Founding seats are limited and locked for life.
Get funding alerts