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Forecasted

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

View forecast on Grants.gov →Forecasted — not yet open

Posted
May 27, 2026
Closes
See announcement
Cost sharing
No
Instrument
Grant
Assistance listing
93.879, 93.361, 93.840, 93.121, 93.350, 93.846, 93.113, 93.213, 93.837, 93.838, 93.859, 93.233, 93.279, 93.866, 93.173, 93.273, 93.839, 93.143, 93.172, 93.847, 93.865, 93.867
Category
Health

Program funding history

Awards made under Assistance Listing 93.879 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$69.5M
FY2025 obligated
$78.9M
FY2026 (to date) obligated
$50.1M
Awards in window
413

Top recipients: The Leland Stanford Junior University, Yale Univ, Trustees of the University of Pennsylvania, the, University of Pittsburgh - of the Commonwealth System of Higher Education, University of Utah

Source: USAspending.gov · refreshed August 2026

Synopsis

The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. Through this NOFO, NIH and CDC will support early-career scientists as they transition into entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project. 

Who can apply

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov

Agency contact: NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER) · [email protected] · 301-827-8595

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