Cancer Cause and Prevention Research

A federal assistance program listed on Grants.gov by National Institutes of Health (Department of Health and Human Services). The listing number stays the same from one funding round to the next, so this page is the one to watch between announcements.

Funding history

Open opportunities under this listing

• Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
  Open RFA-CA-27-020 · closes October 19, 2026
• Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
  Open RFA-CA-27-021 · closes October 19, 2026
• Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
  Open PAR-25-095 · closes November 6, 2026
• Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
  Open PAR-25-096 · closes November 17, 2026
• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)
  Open PAR-24-214 · closes January 7, 2027
• Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
  Open PAR-25-069 · closes January 7, 2027
• Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
  Open PAR-25-070 · closes January 7, 2027
• National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)
  Open PAR-25-081 · closes January 7, 2027
• Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)
  Open PAR-25-167 · closes January 7, 2027
• HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
  Open RFA-NS-25-023 · closes January 15, 2027
• Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)
  Open RFA-CA-28-013 · closes February 9, 2027
• NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
  Open PA-27-100 · closes April 5, 2027
• NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
  Open PA-27-102 · closes April 5, 2027
• Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)
  Open PAR-28-057 · closes May 25, 2027
• Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
  Open PAR-25-210 · closes June 2, 2027
• Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
  Open PAR-25-211 · closes June 2, 2027
• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
  Open PA-24-254 · closes July 12, 2027
• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
  Open PA-24-253 · closes July 17, 2027
• NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
  Open PA-25-080 · closes September 7, 2027
• Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)
  Open PAR-25-325 · closes September 10, 2027
• Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
  Open PAR-25-248 · closes October 8, 2027
• Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
  Open RFA-CA-27-019 · closes October 19, 2027
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)
  Open PAR-27-078 · closes October 25, 2027
• Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
  Open PAR-25-244 · closes November 16, 2027
• Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
  Open PA-25-172 · closes January 7, 2028
• NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
  Open PA-25-301 · closes January 7, 2028
• NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
  Open PA-25-304 · closes January 7, 2028
• NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
  Open PA-25-306 · closes January 7, 2028
• Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)
  Open PAR-24-273 · closes January 7, 2028
• Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
  Open PAR-25-043 · closes January 7, 2028
• Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)
  Open PAR-25-044 · closes January 7, 2028
• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
  Open PAR-25-134 · closes January 7, 2028
• Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)
  Open PAR-25-145 · closes January 7, 2028
• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)
  Open PAR-25-148 · closes January 7, 2028
• Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)
  Open PAR-25-175 · closes January 7, 2028
• Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
  Open PAR-25-243 · closes January 7, 2028
• The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)
  Open PAR-25-292 · closes January 7, 2028
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
  Open PAR-25-298 · closes January 7, 2028
• Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)
  Open PAR-25-321 · closes January 7, 2028
• Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)
  Open PAR-25-346 · closes January 7, 2028
• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
  Open PAR-25-322 · closes August 25, 2028
• Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)
  Open PA-25-253 · closes September 7, 2028
• Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)
  Open PAR-25-324 · closes September 7, 2028
• Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
  Open PA-26-001 · closes November 30, 2028
• NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
  Open PA-27-101 · closes April 5, 2029
• SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)
  Open PAR-27-098 · closes April 5, 2029
• NIH Research Program Projects (Parent P01 Clinical Trial Optional)
  Open PA-27-061 · closes May 25, 2029
• Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)
  Open PAR-28-090 · closes May 25, 2029
• Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)
  Open RFA-AI-27-018 · closes June 20, 2029
• Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)
  Open PAR-27-072 · closes July 5, 2029
• Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)
  Open PAR-27-073 · closes July 5, 2029
• Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (RP1 Clinical Trials Optional)
  Open PAR-28-014 · closes October 11, 2029
• Palliative Care Research Across the Lifespan: Leveraging the Palliative Care Consortium (R01 Clinical Trial Optional)
  Open PAR-27-090 · closes November 5, 2029
• Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)
  Open PAR-28-056 · closes November 5, 2029

Forecasted

• Investigator-Focused Award (Parent R35)
  Forecasted PAR-28-037
• Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
  Forecasted RFA-CA-28-003
• NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)
  Forecasted PAR-27-089
• NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)
  Forecasted PAR-27-088
• Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)
  Forecasted PAR-27-009
• Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)
  Forecasted RFA-CA-26-010

Recently closed

• NCI Community Oncology Research Program (NCORP) Academic Community Sites (UG1 Clinical Trials Not Allowed)
  Closed RFA-CA-27-008 · closed September 18, 2026
• NCI Community Oncology Research Program (NCORP) Community Sites (UG1 Clinical Trial Not Allowed)
  Closed RFA-CA-27-007 · closed September 18, 2026
• NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)
  Closed RFA-CA-27-006 · closed September 18, 2026
• Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
  Closed PAR-24-306 · closed September 7, 2026
• Unveiling Health and Healthcare Disparities in Non-Communicable and Chronic Diseases in Latin America: Setting the Stage for Better Health Outcomes Across the Hemisphere (R01 - Clinical Trials Not Allowed)
  Archived PAR-25-377 · closed June 3, 2026
• National Cancer Institute Program Project Applications for the Years 2023, 2024, and 2025 (P01 Clinical Trial Optional)
  Archived PAR-23-059 · closed May 26, 2026
• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
  Archived PAR-25-323 · closed May 24, 2026
• Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)
  Closed PAR-25-355 · closed January 8, 2026
• Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)
  Closed PAR-25-354 · closed January 8, 2026
• Implementation Research for Multi-morbidity Management in the Context of Non-communicable Diseases in Low- and Middle-Income Countries and US Tribal Populations (R01 Clinical Trial Optional)
  Archived PAR-25-213 · closed January 7, 2026
• Co-infection and Cancer (R01 Clinical Trial Not Allowed)
  Archived PAR-25-082 · closed January 7, 2026
• NCI Small Grants Program for Cancer Research (NCI Omnibus) (R03 Clinical Trial Optional)
  Archived PAR-25-078 · closed January 7, 2026
• Mechanistic links between diet, lipid metabolism, and tumor growth and progression (U01 Clinical Trial Not Allowed)
  Archived PAR-25-119 · closed December 9, 2025
• Mechanistic links between diet, lipid metabolism, and tumor growth and progression (UH2 Clinical Trial Not Allowed)
  Archived PAR-25-118 · closed December 9, 2025
• NCI Research Specialist (Core-based Scientist) Award (R50 Clinical Trial Not Allowed)
  Archived PAR-23-243 · closed December 9, 2025
• NCI Research Specialist (Laboratory-based Scientist) Award (R50 Clinical Trial Not Allowed)
  Archived PAR-23-242 · closed December 9, 2025
• Small Research Grants for Analyses of Gabriella Miller Kids First Pediatric Research Data (R03 Clinical Trial Not Allowed)
  Archived PAR-25-109 · closed November 16, 2025
• HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)
  Archived PAS-22-206 · closed November 12, 2025
• NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)
  Archived PAR-24-274 · closed November 4, 2025
• Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
  Archived PA-20-272 · closed September 29, 2025
• NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional)
  Archived PAR-25-139 · closed September 7, 2025
• Biology of Bladder Cancer (R01 Clinical Trial Optional)
  Archived PAR-25-129 · closed September 7, 2025
• Biology of Bladder Cancer (R21 Clinical Trial Optional)
  Archived PAR-25-128 · closed September 7, 2025
• PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
  Archived PA-24-248 · closed September 5, 2025
• PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
  Archived PA-24-247 · closed September 5, 2025
• PHS 2024-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
  Archived PA-24-246 · closed September 5, 2025
• PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
  Archived PA-24-245 · closed September 5, 2025
• Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
  Archived PAR-23-117 · closed August 4, 2025
• Centers for AIDS Research (P30 Clinical Trial Not Allowed)
  Archived PAR-23-116 · closed August 4, 2025
• Discovery and Development of Natural Products for Cancer Interception and Prevention (UG3/UH3 Clinical Trial Not Allowed)
  Archived RFA-CA-25-013 · closed June 13, 2025
• HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)
  Archived RFA-NS-23-028 · closed June 9, 2025
• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
  Archived PAR-24-076 · closed May 23, 2025
• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
  Archived PAR-24-075 · closed May 23, 2025
• Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
  Archived PAR-23-255 · closed May 23, 2025
• HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional)
  Archived PAR-23-191 · closed May 23, 2025
• Interventions for Stigma Reduction to Improve HIV/AIDS Prevention, Treatment and Care in Low- and Middle- Income Countries (R01 - Clinical Trial Optional)
  Archived PAR-23-190 · closed May 23, 2025
• Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)
  Archived PAR-22-243 · closed May 23, 2025
• Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed)
  Archived PAR-22-242 · closed May 23, 2025
• Imaging, Biomarkers and Digital Pathomics for the Early Detection of Premetastatic Cancer and Precancerous Lesions Associated with Lethal Phenotypes (R01 Clinical Trial Optional)
  Archived PAR-22-131 · closed May 23, 2025
• Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)
  Archived PAR-25-312 · closed May 20, 2025