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Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

Federal funding opportunity PAR-27-072 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes July 5, 2029

Posted
May 4, 2026
Closes
July 5, 2029
Award ceiling
$500,000
Cost sharing
No
Instrument
Grant
Assistance listing
93.399, 93.395, 93.865, 93.867, 93.393, 93.394, 93.396
Category
Health
Archives
September 5, 2029

Program funding history

Awards made under Assistance Listing 93.399 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$167M
FY2025 obligated
$172.1M
FY2026 (to date) obligated
$8.8M
Awards in window
151

Top recipients: Ecog-acrin Medical Research Foundation, Inc., Nrg Oncology Foundation Inc, Alliance Nctn Foundation, Fred Hutchinson Cancer Center, Oregon Health & Science University

Source: USAspending.gov · refreshed July 2026

Synopsis

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · bioengineeringresearchgrants@mail.nih.gov · 301-402-2541

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