Open

Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

Federal funding opportunity PAR-27-072 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes July 5, 2029

Posted: May 4, 2026
Closes: July 5, 2029
Award ceiling: $500,000
Cost sharing: No
Instrument: Grant
Assistance listing: 93.395, 93.393, 93.853, 93.396, 93.399, 93.867, 93.865, 93.394
Category: Health
Archives: September 5, 2029

Program funding history

Awards made under Assistance Listing 93.395 (one of 8 on this opportunity) across FY2025–FY2027, from public federal spending records.

FY2025 obligated: $1.3B
FY2026 obligated: $1.3B
FY2027 (to date) obligated: $0
Awards in window: 3,624

Top recipients: The Univeristy of Texas M.d. Anderson Cancer Center, Dana-farber Cancer Institute, Inc., Icahn School of Medicine at Mount Sinai, Fred Hutchinson Cancer Center, Sloan-kettering Institute for Cancer Research

Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →

Synopsis

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.

Who can apply

Public and State controlled institutions of higher education
County governments
Independent school districts
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
For profit organizations other than small businesses
State governments
City or township governments
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Special district governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations: Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

New to federal funding? How to read an announcement · Who can apply · How grants work

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