NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)
Apply on Grants.gov →Application closes April 5, 2029
- Posted
- May 28, 2026
- Closes
- April 5, 2029
- Cost sharing
- Yes
- Instrument
- Grant
- Assistance listing
- 93.853, 93.838, 93.839, 93.866, 93.307, 93.847, 93.394, 93.837, 93.855, 93.313, 93.393, 93.865, 93.350, 93.242, 93.867, 93.233, 93.351, 93.840, 93.859, 93.273, 93.395
- Category
- Health
- Archives
- June 4, 2029
Program funding history
Awards made under Assistance Listing 93.853 (one of 21 on this opportunity) across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1.8B
- FY2026 obligated
- $2B
- FY2027 (to date) obligated
- $0
- Awards in window
- 8,124
Top recipients: The General Hospital Corporation, Regents of the University of California, San Francisco, the, The Johns Hopkins University, Regents of the University of Michigan, Washington University, the
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
Who can apply
- Small businesses
Only United States small business concerns (SBCs) that have previously received an NIH SBIR or STTR Phase II award are eligible to submit applications for this opportunity. Only one NIH Phase IIB Strategic Breakthrough award is allowed per project. This NOFO supports Renewal/Resubmission "Type 2" Applications from recipients with NIH Phase II SBIR/STTR awards that are submitted within the first six due dates following the expiration of their budget period. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
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