Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
- Posted
- August 25, 2025
- Closed
- May 24, 2026
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.173, 93.865, 93.867, 93.313, 93.866, 93.273, 93.393, 93.361, 93.113, 93.398, 93.879, 93.242, 93.121, 93.846
- Archives
- September 23, 2026
Program funding history
Awards made under Assistance Listing 93.173 (one of 14 on this opportunity) across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $416.1M
- FY2026 obligated
- $414.8M
- FY2027 (to date) obligated
- $0
- Awards in window
- 2,058
Top recipients: The Johns Hopkins University, Massachusetts Eye and Ear Infirmary, University of Pittsburgh - of the Commonwealth System of Higher Education, New York University, The Leland Stanford Junior University
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity Announcement (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies that are NOT conducted with specific applications toward processes or products in mind and which also do not meet the clinical trial definition should submit under the appropriate Clinical Trial Not Allowed NOFO .
Who can apply
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Independent school districts
- State governments
- City or township governments
- Native American tribal governments (Federally recognized)
- County governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- Public and State controlled institutions of higher education
- For profit organizations other than small businesses
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
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