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SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Federal funding opportunity PAR-27-098 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes April 5, 2029

Posted
May 28, 2026
Closes
April 5, 2029
Cost sharing
No
Instrument
Grant
Assistance listing
93.307, 93.313, 93.865, 93.838, 93.242, 93.233, 93.273, 93.173, 93.853, 93.393, 93.395, 93.350, 93.866, 93.121, 93.867, 93.113, 93.855, 93.859, 93.172, 93.839, 93.840, 93.286, 93.846, 93.143, 93.351, 93.394, 93.837, 93.847
Category
Health
Archives
June 4, 2029

Program funding history

Awards made under Assistance Listing 93.307 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$442.2M
FY2025 obligated
$438.1M
FY2026 (to date) obligated
$186.8M
Awards in window
1,235

Top recipients: The Trustees of Columbia University in the City of New York, The Johns Hopkins University, Regents of the University of California, San Francisco, the, University of Hawaii, San Diego State University Foundation

Source: USAspending.gov · refreshed July 2026

Synopsis

The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical assistance that Phase II and Phase IIB Strategic Breakthrough awards do not typically support. This includes:Independent replication or confirmation of key studiesIND- or IDE-enabling studiesClinical studiesManufacturing scale-up and related quality activitiesRegulatory and other specialized technical supportSBCs may subcontract (outsource) a significant amount of the work in a CRP to meet the project goals.

Who can apply

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · SEEDinfo@nih.gov · 301-402-2541

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