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NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

Federal funding opportunity PAR-25-026 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes January 7, 2027

Posted
December 5, 2024
Closes
January 7, 2027
Cost sharing
No
Instrument
Grant
Assistance listing
93.840, 93.233, 93.839, 93.837, 93.838
Category
Health
Archives
February 12, 2027

Program funding history

Awards made under Assistance Listing 93.840 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$1.2M
FY2025 obligated
$2.1M
FY2026 (to date) obligated
$0
Awards in window
88

Top recipients: The Regents of the University of Colorado, Indiana Department of Health, Minnesota Department of Health, Michigan Public Health Institute, City of Philadelphia

Source: USAspending.gov · refreshed July 2026

Synopsis

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will utilize a bi-phasic, milestone-driven mechanism of award where the first phase can be used to finalize required pre-trial activities such as stability, shipping studies, and site training.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov   Full announcement

Agency contact: National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

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