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NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

Federal funding opportunity PAR-25-025 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes January 7, 2027

Posted
December 5, 2024
Closes
January 7, 2027
Award ceiling
$1,515,000
Cost sharing
No
Instrument
Grant
Assistance listing
93.838, 93.839, 93.233, 93.837
Category
Health
Archives
February 12, 2027

Program funding history

Awards made under Assistance Listing 93.838 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$-47,224
FY2025 obligated
$-250,767
FY2026 (to date) obligated
$0
Awards in window
1,105

Top recipients: Rutgers, the State University, University of Rochester, Trustees of Indiana University, National Jewish Health, The Trustees of Columbia University in the City of New York

Source: USAspending.gov · refreshed July 2026

Synopsis

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be established by the time of award. If time and support for these and other pre-clinical and/or trial readiness activities are desired, applicants should consider the companion NOFO which utilizes an R61/R33 phased approach.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov   Full announcement

Agency contact: National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

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