Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

Federal funding opportunity PAR-27-011 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes November 2, 2028

Program funding history

Synopsis

Who can apply

• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• Special district governments
• Public and State controlled institutions of higher education
• Public housing authorities/Indian housing authorities
• County governments
• City or township governments
• Private institutions of higher education
• Independent school districts
• Native American tribal organizations (other than Federally recognized tribal governments)
• Native American tribal governments (Federally recognized)
• State governments
• For profit organizations other than small businesses
• Small businesses

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

How to apply

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