Closed

HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Clinical Trial Center and Clinical Centers (U01 Clinical Trial Optional)

Federal funding opportunity RFA-HL-27-008 from National Institutes of Health (Department of Health and Human Services).

Posted: May 19, 2026
Closes: July 9, 2026
Award ceiling: $500,000
Program funding: $3,465,000
Expected awards: 8
Cost sharing: No
Instrument: Cooperative Agreement
Assistance listing: 93.837
Category: Health
Archives: September 7, 2026

Program funding history

Awards made under Assistance Listing 93.837 across FY2024–FY2026, from public federal spending records.

FY2024 obligated: $3B
FY2025 obligated: $3B
FY2026 (to date) obligated: $1.9B
Awards in window: 12,285

Top recipients: Brigham & Womens Hospital Inc, Trustees of the University of Pennsylvania, the, Regents of the University of Michigan, The Leland Stanford Junior University, The Johns Hopkins University

Source: USAspending.gov · refreshed August 2026

This opportunity is closed. Applications are no longer accepted. Similar open grants are listed below, and the free Tuesday digest carries the next ones like it.

Synopsis

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for a new Clinical Trial Center (CTC) and up to seven Clinical Centers (CCs) for the HeartShare 2.0 program. The CTC will coordinate precision clinical trial activities focused on heart failure with preserved ejection fraction (HFpEF), including master protocol development, project management, recruitment oversight, performance milestones, and scientific conduct of trials. The CCs will recruit and retain heart failure patients and controls. The CCs will participate in all aspects of conducting a deep phenotyping protocol and longitudinal follow-up of HFpEF patients; obtaining tissue biopsies; and recruiting patients for future clinical trials.Eligible applicants may submit proposals for either the CTC or CC, but must have different PIs. Each application should include CTC or CC as part of their project title.Companion NOFO for RFA-HL-27-009 will support a Data Translation Center (DTC) for overall coordination of the HeartShare program.

Who can apply

City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Special district governments
Private institutions of higher education
For profit organizations other than small businesses
State governments
Small businesses

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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