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Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)

Federal funding opportunity RFA-DK-27-119 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes February 10, 2027

Posted
June 16, 2026
Closes
February 10, 2027
Award ceiling
$750,000
Program funding
$4,800,000
Expected awards
4
Cost sharing
No
Instrument
Grant
Assistance listing
93.847
Category
Health
Archives
April 10, 2027

Program funding history

Awards made under Assistance Listing 93.847 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$1.9B
FY2025 obligated
$2B
FY2026 (to date) obligated
$1B
Awards in window
8,079

Top recipients: Regents of the University of Michigan, Trustees of the University of Pennsylvania, the, Washington University, the, University of Pittsburgh - of the Commonwealth System of Higher Education, Regents of the University of California, San Francisco, the

Source: USAspending.gov · refreshed July 2026

Synopsis

This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Only institutions at which there is a strong ongoing base of digestive and/or liver diseases-relevant research that relates to the proposed theme of the Center are eligible. The already funded research base must have at least $3 million per year in direct costs of supported research within a proposed theme area that is of primary interest to the NIDDK. These may be a mix of Federal and privately funded research awards or research career development awards. However, at least 30 percent of the total funding contributing to the research base must be secured from the NIDDK. Moreover, enough awards within the research base must be Federal to fulfill the requirement that each Biomedical Research Core must be utilized by a minimum of two federally funded Center members. Training grants, education grants, and fellowship awards are not considered part of the research base funding. Since "Facilities and Administration" costs vary considerably between institutions, these must not be included in the calculation of the research base.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · NIDDK_DDN@nih.gov · 301-402-2541

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