Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research
Federal funding opportunity RFA-DK-27-102 from National Institutes of Health.
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- September 26, 2025
- Closes
- See announcement
- Program funding
- $1,000,000
- Expected awards
- 4
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.847
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.847 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $1.9B
- FY2025 obligated
- $2B
- FY2026 (to date) obligated
- $1B
- Awards in window
- 8,079
Top recipients: Regents of the University of Michigan, Trustees of the University of Pennsylvania, the, Washington University, the, University of Pittsburgh - of the Commonwealth System of Higher Education, Regents of the University of California, San Francisco, the
Source: USAspending.gov · refreshed July 2026
Synopsis
The National Institute of Diabetes and Digestive and Kidney Diseases intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on microphysiological systems (MPSs) to model type 2 diabetes. Advances in biomaterials, microfluidics, and tissue engineering have resulted in MPSs that allow for greater control of three-dimensional cell cultures containing multiple cell types and constituting more physiological tissue organization. The utility of these systems lends themselves to powerful in vitro modeling of metabolic tissue crosstalk, study of basic mechanisms of human type 2 diabetes, and the testing of prevention and treatment strategies. MPSs are especially useful for investigating the heterogeneity of human T2D biology and clinical responses. The current initiative will support small pilot studies to conceptualize aspects of T2D biology for modeling with MPSs, to support feasibility studies, and to generate preliminary data. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Collaborative investigations combining expertise in bioengineering, type 2 diabetes biology, and human metabolism will be encouraged and these investigators should begin considering applying for this application.
Who can apply
- Public housing authorities/Indian housing authorities
- For profit organizations other than small businesses
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Special district governments
- Small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Native American tribal organizations (other than Federally recognized tribal governments)
- State governments
- City or township governments
- County governments
- Private institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source.
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