Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research
- Posted
- September 26, 2025
- Closed
- See announcement
- Program funding
- $1,000,000
- Expected awards
- 4
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.847
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.847 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $2B
- FY2026 obligated
- $2B
- FY2027 (to date) obligated
- $0
- Awards in window
- 7,162
Top recipients: Regents of the University of Michigan, Trustees of the University of Pennsylvania, the, Regents of the University of California, San Francisco, the, University of Pittsburgh - of the Commonwealth System of Higher Education, University of South Florida
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The National Institute of Diabetes and Digestive and Kidney Diseases intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on microphysiological systems (MPSs) to model type 2 diabetes. Advances in biomaterials, microfluidics, and tissue engineering have resulted in MPSs that allow for greater control of three-dimensional cell cultures containing multiple cell types and constituting more physiological tissue organization. The utility of these systems lends themselves to powerful in vitro modeling of metabolic tissue crosstalk, study of basic mechanisms of human type 2 diabetes, and the testing of prevention and treatment strategies. MPSs are especially useful for investigating the heterogeneity of human T2D biology and clinical responses. The current initiative will support small pilot studies to conceptualize aspects of T2D biology for modeling with MPSs, to support feasibility studies, and to generate preliminary data. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Collaborative investigations combining expertise in bioengineering, type 2 diabetes biology, and human metabolism will be encouraged and these investigators should begin considering applying for this application.
Who can apply
- Public housing authorities/Indian housing authorities
- For profit organizations other than small businesses
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Special district governments
- Small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Native American tribal organizations (other than Federally recognized tribal governments)
- State governments
- City or township governments
- County governments
- Private institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
New to federal funding? How to read an announcement · Who can apply · How grants work
Tell me when this program posts again
This round has closed. One email the morning after this program is posted again under a new number (we watch for about two years), and one more about a week before that round closes (the next morning, if it is already closer than that). That is all this sends — it is not a newsletter signup.
Get grants like this every Tuesday — free
One email a week: the biggest new federal grants and what’s closing soon — the same list for everyone. Unsubscribe any time.
Similar grants
- Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)
- Rigor and Reproducibility for Biomarkers in Type 1 Diabetes Clinical Research
- Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
- Diabetes Research Centers (P30 Clinical Trial Optional)
- Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
- Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)
Same-day alerts, matched to you
The free digest is weekly — the same list for everyone. Members get every open federal grant scored to their organization — and an alert the day a real match posts: we read every new posting the day it opens. Free for 30 days, then $29/mo. Card required, cancel any time before day 31.
Not ready for a subscription? A one-time Fit Report — $29 — scores every open federal grant to your organization once, by email within one business day.
See pricing