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Metastasis Research Network (U54 Clinical Trial Not Allowed)

Federal funding opportunity RFA-CA-27-012 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes September 25, 2026

Posted: June 4, 2026
Closes: September 25, 2026
Award ceiling: $1,300,000
Program funding: $6,800,000
Expected awards: 4
Cost sharing: No
Instrument: Cooperative Agreement
Assistance listing: 93.396
Category: Health
Archives: November 24, 2026

Program funding history

Awards made under Assistance Listing 93.396 across FY2024–FY2026, from public federal spending records.

FY2024 obligated: $872.6M
FY2025 obligated: $914.3M
FY2026 (to date) obligated: $668.2M
Awards in window: 3,407

Top recipients: The Trustees of Columbia University in the City of New York, The Univeristy of Texas M.d. Anderson Cancer Center, Sloan-kettering Institute for Cancer Research, Trustees of the University of Pennsylvania, the, Weill Medical College of Cornell University

Source: USAspending.gov · refreshed August 2026

Synopsis

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the NCI will support U54 Specialized Centers that together will continue to serve as the hub of the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. The projects should use integrative system level approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elements in the metastatic process such as early dissemination, cellular, soluble and/or physical microenvironment crosstalk, dormancy, or mechanisms of responses by metastatic cells to therapies. Studies on all types of cancer are welcome, including rare and pediatric metastatic cancers.Research proposed by MetNet Centers is expected to advance our understanding towards a more comprehensive appreciation of metastasis as a whole body, systems-level problem.

Who can apply

Native American tribal organizations (other than Federally recognized tribal governments)
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
For profit organizations other than small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
County governments
City or township governments
Independent school districts
Special district governments
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Public housing authorities/Indian housing authorities
Private institutions of higher education

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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