Centers for Structural Biology of HIV and other Infectious Diseases
Federal funding opportunity RFA-AI-27-009 from National Institutes of Health.
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- December 22, 2025
- Closes
- See announcement
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.855
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.855 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $4.1B
- FY2025 obligated
- $4.2B
- FY2026 (to date) obligated
- $2.3B
- Awards in window
- 14,249
Top recipients: Fred Hutchinson Cancer Center, The Johns Hopkins University, Regents of the University of California, San Francisco, the, Washington University, the, Duke University
Source: USAspending.gov · refreshed July 2026
Synopsis
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting the Centers for Structural Biology of HIV and other Infectious Diseases. This solicitation will support multidisciplinary groups of scientists to determine the 3-dimensional structures of molecules and molecular complexes involved in priority infectious diseases. The effort focuses on exploring biomolecular complexes that can be targeted to make new medicines and tests to prevent or treat infections and improve human health. The centers will drive cutting-edge research and development of structural biology technologies, including high-resolution 3D structural analyses, computational molecular dynamics, functional and mechanistic characterization at the molecular and cellular level, visualization at the atomic level of molecular complexes in cells and tissues, and advanced structure-guided design of molecules to combat infectious diseases. The centers will maximize use of common resources, establish broad collaborations, and mentor future structural biology researchers. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply
- State governments
- Special district governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal governments (Federally recognized)
- City or township governments
- For profit organizations other than small businesses
- Small businesses
- Independent school districts
- Public housing authorities/Indian housing authorities
- County governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Private institutions of higher education
- Public and State controlled institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
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