Feasibility Studies to Inform the Design of Future Clinical Trials
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- April 28, 2026
- Closes
- See announcement
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.213
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.213 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $118.3M
- FY2025 obligated
- $115.4M
- FY2026 (to date) obligated
- $53.3M
- Awards in window
- 697
Top recipients: University of California, San Diego, The General Hospital Corporation, Yale Univ, Regents of the University of California, San Francisco, the, The Spaulding Rehabilitation Hospital Corporation
Source: USAspending.gov · refreshed August 2026
Synopsis
The National Institutes of Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose feasibility studies that could inform the design and conduct of subsequent definitive clinical trials (e.g., efficacy, effectiveness, pragmatic, dissemination and implementation, phase/stage II or later trials). Applications to this NOFO should demonstrate that the proposed feasibility research is scientifically necessary to design or plan the subsequent definitive clinical trial. Studies may utilize mixed methods and feasibility clinical trials to assess feasibility of recruitment, randomization, retention, intervention delivery, data collection, adherence, acceptability, and/or develop or adapt intervention components or protocols. The proposed feasibility research should enhance the rigor and reproducibility of the future trial methods. The subsequent definitive clinical trial should have the potential to make a significant impact on public health.
Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise in clinical trial planning, design, implementation, intervention development, and/or stakeholder engagement are encouraged to begin to consider applying for this new NOFO.
Who can apply
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- City or township governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- County governments
- Independent school districts
- State governments
- For profit organizations other than small businesses
- Small businesses
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized tribal governments)
- Special district governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities/Indian housing authorities
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
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