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Forecasted

Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (Clinical Trials Optional)

Federal funding opportunity PAR-26-128 from National Institutes of Health.

View forecast on Grants.gov →Forecasted — not yet open

Posted
March 9, 2026
Closes
See announcement
Cost sharing
No
Instrument
Grant
Assistance listing
93.350
Category
Health

Program funding history

Awards made under Assistance Listing 93.350 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$588.2M
FY2025 obligated
$599.3M
FY2026 (to date) obligated
$281.4M
Awards in window
886

Top recipients: Vanderbilt University Medical Center, Regents of the University of Michigan, University of Pittsburgh - of the Commonwealth System of Higher Education, Icahn School of Medicine at Mount Sinai, The Johns Hopkins University

Source: USAspending.gov · refreshed July 2026

Synopsis

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded Clinical and Translational Science Awards (CTSA) Program Hubs. Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program Hubs.

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Who can apply

All applicant organizations and/or active award recipients for PAR-24-272 Clinical and Translational Science Award (UM1 Clinical Trial Optional) are eligible to apply for Specialized Innovation Programs (SIPs) under this NOFO. Only the primary UM1 CTSA program hub organization is eligible to apply (not partner or collaborator institutions).Companion optional applications may be submitted under the following scenarios:-concurrently with the UM1-while the UM1 application is under review consideration-after the UM1 application is funded-while the UM1 is under consideration for fundingApplications will only be awarded if there is an awarded UM1 application from the applicant organization.Other information on eligibility and number of applications:An active (not in an extension period) UM1 hub institution can submit up to two applications for SIPs per cycle as the primary institution.A CTSA UM1 hub may have up to two SIPs awards as the primary recipient at a given time.No more than two applications may be submitted by a UM1 hub as a primary per application due date and no more than two applications may be awarded to an active (not in an extension period) CTSA UM1 hub as a primary recipient, at a given time.A UM1 hub that is in an extension period is not allowed to submit an application as the primary institution unless a pending UM1 application has been submitted or is under review or funding consideration. Resubmission of a application without the required UM1 application is only allowed if the companion UM1 application is awarded.For the purpose of this NOFO, SIPs awarded in an extension period count towards the maximum of two SIP awards that may be awarded to an active UM1 hub as a primary, at a given time.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: CTSA Program Branch, Division of Clinical Innovation · RC2NOFO@nih.gov · 301-827-2017

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