Interdisciplinary Research to Understand the Complex Biology of Resilience to Alzheimer’s and Related Dementias Disease Risk
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- September 3, 2025
- Closes
- See announcement
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.866
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.866 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $3.8B
- FY2025 obligated
- $3.9B
- FY2026 (to date) obligated
- $2.4B
- Awards in window
- 12,121
Top recipients: Regents of the University of Michigan, Regents of the University of California, San Francisco, the, Washington University, the, The Trustees of Columbia University in the City of New York, University of Southern California
Source: USAspending.gov · refreshed August 2026
Synopsis
The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) that builds upon its investment in data-driven approaches for the purpose of defining molecular mechanisms of resilience in the presence of various types of Alzheimer's disease (AD) and AD-related dementias (ADRD) risk. The goal of this NOFO is to build a robust program that integrates epidemiologic, genomic, and mechanistic research through the use of data driven, systems-based approaches (including the use of artificial intelligence and/or machine learning methods) to discover the molecular/cellular determinants of resilience to AD/ADRD risk across representative populations. The initiative will support the generation of high-dimensional molecular data from brain and peripheral tissues, including longitudinal data, to enable dynamic modeling of resilience mechanisms and to discover molecular predictors of resilience.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
Who can apply
- Native American tribal organizations (other than Federally recognized tribal governments)
- Private institutions of higher education
- Public housing authorities/Indian housing authorities
- Special district governments
- For profit organizations other than small businesses
- Small businesses
- State governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Independent school districts
- County governments
- Public and State controlled institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- City or township governments
- Native American tribal governments (Federally recognized)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
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