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Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)

Federal funding opportunity PAR-25-256 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes January 7, 2027

Posted
November 15, 2024
Closes
January 7, 2027
Cost sharing
No
Instrument
Grant
Assistance listing
93.399, 93.172
Category
Education, Health
Archives
February 12, 2027

Program funding history

Awards made under Assistance Listing 93.399 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$167M
FY2025 obligated
$172.1M
FY2026 (to date) obligated
$8.8M
Awards in window
151

Top recipients: Ecog-acrin Medical Research Foundation, Inc., Nrg Oncology Foundation Inc, Alliance Nctn Foundation, Fred Hutchinson Cancer Center, Oregon Health & Science University

Source: USAspending.gov · refreshed July 2026

Synopsis

The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov   Full announcement

Agency contact: National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

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