Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
Federal funding opportunity PAR-25-101 from National Institutes of Health (Department of Health and Human Services).
Apply on Grants.gov →Application closes August 11, 2027
- Posted
- December 30, 2024
- Closes
- August 11, 2027
- Award ceiling
- $150,000
- Program funding
- $150,000
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.279
- Archives
- September 16, 2027
Program funding history
Awards made under Assistance Listing 93.279 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $1.5B
- FY2025 obligated
- $1.5B
- FY2026 (to date) obligated
- $754.3M
- Awards in window
- 5,529
Top recipients: Yale Univ, University of California, San Diego, The Johns Hopkins University, University of Pittsburgh - of the Commonwealth System of Higher Education, Regents of the University of Michigan
Source: USAspending.gov · refreshed July 2026
Synopsis
The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.
Who can apply
- State governments
- Small businesses
- Public and State controlled institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Special district governments
- County governments
- Independent school districts
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- For profit organizations other than small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Native American tribal governments (Federally recognized)
- City or township governments
- Private institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source.
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