Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed)
- Posted
- April 25, 2024
- Closed
- November 17, 2025
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.172, 93.859, 93.273, 93.233, 93.350, 93.865, 93.143, 93.361, 93.113, 93.879, 93.867, 93.866, 93.840, 93.173, 93.279, 93.213, 93.838, 93.846, 93.847, 93.837, 93.839, 93.262, 93.121
- Archives
- November 18, 2025
Program funding history
Awards made under Assistance Listing 93.172 (one of 23 on this opportunity) across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $420.8M
- FY2026 obligated
- $445M
- FY2027 (to date) obligated
- $0
- Awards in window
- 1,087
Top recipients: The Leland Stanford Junior University, The Broad Institute, Inc, University of Washington, University of North Carolina at Chapel Hill, Jackson Laboratory
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
Through this Notice of Funding Opportunity (NOFO), the National Institutes of Health (NIH) aims to facilitate the career development and transition of investigators new to entrepreneurship with an interest in small business by simultaneously supporting their entrepreneurial development and the conduct of research and development under their direction. This NOFO supports small business concerns (SBCs) in employing and developing researchers as entrepreneurial Program Directors/Principal Investigators (PDs/PIs). In addition to augmenting scientific research staff and supporting research and development efforts at SBCs, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Optimal PDs/PIs for this award are scientists and professionals with strong research, technology development, and/or healthcare delivery skills and experience, but limited entrepreneurial and independent research project leadership experience. PDs/PIs are expected to grow their entrepreneurial skillset while working in a small business to develop promising technologies and products that align with NIH's mission to improve health and save lives.
Who can apply
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- County governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Native American tribal governments (Federally recognized)
- State governments
- City or township governments
- Independent school districts
- Public and State controlled institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
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