Archived

BRAIN Initiative: Scaled reagent resources for brain cell type-specific access across vertebrate species (U01 Clinical Trial Not Allowed)

Federal funding opportunity RFA-MH-25-100 from National Institutes of Health (Department of Health and Human Services).

Posted: February 20, 2024
Closed: January 17, 2025
Cost sharing: No
Instrument: Cooperative Agreement
Assistance listing: 93.213, 93.173, 93.866, 93.279, 93.865, 93.273, 93.867, 93.853, 93.286, 93.242
Category: Education, Health, Income Security and Social Services
Archives: February 22, 2025

Program funding history

Awards made under Assistance Listing 93.213 (one of 10 on this opportunity) across FY2025–FY2027, from public federal spending records.

FY2025 obligated: $115.4M
FY2026 obligated: $119M
FY2027 (to date) obligated: $0
Awards in window: 635

Top recipients: University of California, San Diego, The General Hospital Corporation, Yale Univ, The Spaulding Rehabilitation Hospital Corporation, University of California Irvine

Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →

This opportunity is archived. Applications are no longer accepted. Similar grants are listed below, and the free Tuesday digest carries the next ones like it.

Synopsis

This BRAIN Initiative Notice of Funding Opportunity (NOFO) is to scale up efforts for viral, non-viral, transgenic, and gene regulatory element screening technologies and create reagent resources to access brain cell types. This NOFO is part of the BRAIN Initiative Armamentarium for Brain Cell Access transformative project. Reagent development efforts will apply gene transfer, gene regulation, genome engineering, activity sensor/effector, and atlasing technologies for use in both genetically tractable and less tractable systems, including primates and human tissue, which are relevant for future translational efforts. Reagent validation studies will provide feedback to improve scaled resources, informed by deeper understanding of neural gene transfer and regulation mechanisms. Precise targeting could ultimately aid in human disorders, for example, by providing access for gene editors to specific cell types to repair mutations.

Who can apply

Public housing authorities/Indian housing authorities
Independent school districts
City or township governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Native American tribal governments (Federally recognized)
Special district governments
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
For profit organizations other than small businesses
County governments
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

The official record

Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.

View on Grants.gov Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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