Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)
Apply on Grants.gov →Application closes September 25, 2029
- Posted
- October 14, 2026
- Closes
- September 25, 2029
- Program funding
- $1,400,000
- Expected awards
- 10
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.121, 93.395
- Category
- Health
- Archives
- November 25, 2029
Program funding history
Awards made under Assistance Listing 93.121 (one of 2 on this opportunity) across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $378.9M
- FY2026 obligated
- $380.8M
- FY2027 (to date) obligated
- $0
- Awards in window
- 2,170
Top recipients: Regents of the University of California, San Francisco, the, Regents of the University of Michigan, University of Pittsburgh - of the Commonwealth System of Higher Education, University of Florida, University of Southern California
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPOREs). Based on the proposed research, applications may be jointly funded with the National Institute of Dental and Craniofacial Research (NIDCR). This is a re-issuance of PAR-23-284. The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. The research supported through this program must be translational and be based on human biology research using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must reach a translational human endpoint within the project period of the grant.
Who can apply
- Public housing authorities/Indian housing authorities
- For profit organizations other than small businesses
- Independent school districts
- Special district governments
- State governments
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Small businesses
- City or township governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Native American tribal governments (Federally recognized)
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- County governments
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations: Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
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