Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Federal funding opportunity PAR-25-450 from National Institutes of Health (Department of Health and Human Services).
Apply on Grants.gov →Application closes July 20, 2028
- Posted
- September 22, 2025
- Closes
- July 20, 2028
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.350, 93.865
- Archives
- August 25, 2028
Program funding history
Awards made under Assistance Listing 93.350 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $588.2M
- FY2025 obligated
- $599.3M
- FY2026 (to date) obligated
- $281.4M
- Awards in window
- 886
Top recipients: Vanderbilt University Medical Center, Regents of the University of Michigan, University of Pittsburgh - of the Commonwealth System of Higher Education, Icahn School of Medicine at Mount Sinai, The Johns Hopkins University
Source: USAspending.gov · refreshed July 2026
Synopsis
Who can apply
- Small businesses
- Independent school districts
- County governments
- Public and State controlled institutions of higher education
- State governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- City or township governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Special district governments
- For profit organizations other than small businesses
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source.
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