Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- August 13, 2026
- Closes
- See announcement
- Expected awards
- 15
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.853
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.853 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1.8B
- FY2026 obligated
- $2B
- FY2027 (to date) obligated
- $0
- Awards in window
- 8,124
Top recipients: The General Hospital Corporation, Regents of the University of California, San Francisco, the, The Johns Hopkins University, Regents of the University of Michigan, Washington University, the
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care.
Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Who can apply
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- State governments
- City or township governments
- Public and State controlled institutions of higher education
- Independent school districts
- Public housing authorities/Indian housing authorities
- Native American tribal governments (Federally recognized)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
New to federal funding? How to read an announcement · Who can apply · How grants work
Tell me when this program posts again
One email the morning after this program opens for applications — under this number or a new one — and one more about a week before it closes (the next morning, if it is already closer than that). That is all this sends — it is not a newsletter signup.
Get grants like this every Tuesday — free
One email a week: the biggest new federal grants and what’s closing soon — the same list for everyone. Unsubscribe any time.
Similar grants
- Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)
- Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Research Sites (U24 Clinical Trial Not Allowed)
- NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – Regional Coordinating Stroke Centers (RCCs)
- Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Coordinating Center (CCC) & Data Coordinating Center (DCC)
- NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC)
- NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
Same-day alerts, matched to you
The free digest is weekly — the same list for everyone. Members get every open federal grant scored to their organization — and an alert the day a real match posts: we read every new posting the day it opens. Free for 30 days, then $29/mo. Card required, cancel any time before day 31.
Not ready for a subscription? A one-time Fit Report — $29 — scores every open federal grant to your organization once, by email within one business day.
See pricing