Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- August 13, 2026
- Closes
- See announcement
- Expected awards
- 15
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.853
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.853 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $1.8B
- FY2025 obligated
- $1.8B
- FY2026 (to date) obligated
- $1.4B
- Awards in window
- 9,485
Top recipients: The General Hospital Corporation, Regents of the University of California, San Francisco, the, The Johns Hopkins University, Regents of the University of Michigan, The Trustees of Columbia University in the City of New York
Source: USAspending.gov · refreshed August 2026
Synopsis
The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care.
Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Who can apply
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- State governments
- City or township governments
- Public and State controlled institutions of higher education
- Independent school districts
- Public housing authorities/Indian housing authorities
- Native American tribal governments (Federally recognized)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
New to federal funding? How to read an announcement · Who can apply · How grants work
Get grants like this every Tuesday — free
One email a week: the biggest new federal grants and what’s closing soon — the same list for everyone. Unsubscribe in one click.
Similar grants
- Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
- Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
- Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
- Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
- Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
- Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
Same-day alerts, matched to you
The free digest is weekly — the same list for everyone. Members get an alert the day a matching federal grant posts: we read every new Grants.gov posting and score it, personalized to your organization. Free for 30 days, then $19/mo founding rate locked for life — the rate holds while your subscription stays active (Terms). Card required, cancel any time before day 31.
See pricing