Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- August 13, 2026
- Closes
- See announcement
- Expected awards
- 2
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.853
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.853 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1.8B
- FY2026 obligated
- $2B
- FY2027 (to date) obligated
- $0
- Awards in window
- 8,124
Top recipients: The General Hospital Corporation, Regents of the University of California, San Francisco, the, The Johns Hopkins University, Regents of the University of Michigan, Washington University, the
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue support for the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care. The program will encourage applications for a clinical coordinating center (CCC) and data coordinating center (DCC) to support the NIH SIREN clinical trial network.
Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Who can apply
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Public housing authorities/Indian housing authorities
- Private institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- For profit organizations other than small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- Small businesses
- Special district governments
- County governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.
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Similar grants
- Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs
- Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Coordinating Center (CCC) & Data Coordinating Center (DCC)
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- Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center
- NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – Regional Coordinating Stroke Centers (RCCs)
- Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Research Sites (U24 Clinical Trial Not Allowed)
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