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GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Federal funding opportunity RFA-HG-27-012 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes October 30, 2026

Posted: June 18, 2026
Closes: October 30, 2026
Award ceiling: $2,250,000
Program funding: $3,000,000
Expected awards: 1
Cost sharing: No
Instrument: Cooperative Agreement
Assistance listing: 93.172
Category: Health
Archives: December 29, 2026

Program funding history

Awards made under Assistance Listing 93.172 across FY2024–FY2026, from public federal spending records.

FY2024 obligated: $441.6M
FY2025 obligated: $420.8M
FY2026 (to date) obligated: $306.8M
Awards in window: 1,280

Top recipients: The Leland Stanford Junior University, The Broad Institute, Inc, University of Washington, Jackson Laboratory, University of North Carolina at Chapel Hill

Source: USAspending.gov · refreshed August 2026

Synopsis

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

Who can apply

Independent school districts
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Native American tribal organizations (other than Federally recognized tribal governments)
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
Private institutions of higher education
Special district governments
County governments
State governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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