Open

Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)

Federal funding opportunity RFA-DA-26-056 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes December 3, 2027

Posted: December 5, 2024
Closes: December 3, 2027
Cost sharing: No
Instrument: Grant
Assistance listing: 93.273, 93.279
Category: Education, Health
Archives: January 8, 2028

Program funding history

Awards made under Assistance Listing 93.273 (one of 2 on this opportunity) across FY2025–FY2027, from public federal spending records.

FY2025 obligated: $449M
FY2026 obligated: $461.5M
FY2027 (to date) obligated: $0
Awards in window: 2,078

Top recipients: Yale Univ, Trustees of Indiana University, University of North Carolina at Chapel Hill, University of California, San Diego, University of Washington

Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →

Synopsis

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV.

Who can apply

Others (see text field entitled "Additional Information on Eligibility" for clarification)
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
County governments
Public and State controlled institutions of higher education
State governments
Small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
Independent school districts
Private institutions of higher education
For profit organizations other than small businesses
City or township governments

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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