Archived

HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)

Federal funding opportunity RFA-DA-25-078 from National Institutes of Health (Department of Health and Human Services).

Posted: December 17, 2024
Closed: March 20, 2025
Expected awards: 12
Cost sharing: No
Instrument: Grant
Assistance listing: 93.242, 93.279, 93.273, 93.213, 93.865, 93.866
Category: Education, Health, Income Security and Social Services
Archives: April 25, 2025

Program funding history

Awards made under Assistance Listing 93.242 (one of 6 on this opportunity) across FY2025–FY2027, from public federal spending records.

FY2025 obligated: $1.8B
FY2026 obligated: $1.8B
FY2027 (to date) obligated: $0
Awards in window: 6,272

Top recipients: Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, Icahn School of Medicine at Mount Sinai, Trustees of the University of Pennsylvania, the, Washington University, the

Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →

This opportunity is archived. Applications are no longer accepted. Similar grants are listed below, and the free Tuesday digest carries the next ones like it.

Synopsis

This RFA will act as a parent RFA for the HEAL initiative Translation to Practice Team, specifically encouraging translational dissemination and implementation research focused on addressing overdose deaths and the intersection of pain and OUD. This RFA will function in tandem with targeted NOSIs that announce more specific areas of focus. For FY25, this currently includes the Workforce NOSI, the Exposure to Violence NOSI, and the Leveraging Inpatient Hospitalizations NOSI. It has a companion R33 RFA.

Who can apply

City or township governments
County governments
Public and State controlled institutions of higher education
For profit organizations other than small businesses
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Public housing authorities/Indian housing authorities
Independent school districts
Native American tribal governments (Federally recognized)
Special district governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

The official record

Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.

View on Grants.gov Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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Similar grants

HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)
RFA-DA-27-016 · National Institutes of Health · closes February 9, 2029
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
RFA-AT-25-003 · National Institutes of Health · closes November 23, 2026
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
RFA-DA-28-011 · National Institutes of Health · closes January 26, 2027
HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
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NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
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Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
PAR-25-370 · National Institutes of Health · closes November 16, 2026

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