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Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)

Apply on Grants.gov →Application closes September 7, 2026

Posted
November 18, 2024
Closes
September 7, 2026
Cost sharing
No
Instrument
Grant
Assistance listing
93.866, 93.242
Category
Health
Archives
October 13, 2026

Program funding history

Awards made under Assistance Listing 93.866 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$3.8B
FY2025 obligated
$3.9B
FY2026 (to date) obligated
$2.4B
Awards in window
12,121

Top recipients: Regents of the University of Michigan, Regents of the University of California, San Francisco, the, Washington University, the, The Trustees of Columbia University in the City of New York, University of Southern California

Source: USAspending.gov · refreshed August 2026

Synopsis

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). The findings are expected to advanceadavnce mechanistic understanding of both biobehavioral and neurobiologfical pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD.

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov   Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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