Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)

Federal funding opportunity PAR-24-326 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes June 1, 2027

Posted: October 29, 2024
Closes: June 1, 2027
Cost sharing: No
Instrument: Grant
Assistance listing: 93.351, 93.859
Category: Health
Archives: July 7, 2027

Program funding history

Awards made under Assistance Listing 93.351 across FY2024–FY2026, from public federal spending records.

FY2024 obligated: $279M
FY2025 obligated: $281.4M
FY2026 (to date) obligated: $138.1M
Awards in window: 1,100

Top recipients: University of California, Davis, Oregon Health & Science University, University of Washington, Emory University, Texas Biomedical Research Institute

Source: USAspending.gov · refreshed July 2026

Synopsis

The Basic Instrumentation Grant (BIG) Program encourages applications from groups of NIH-supported investigators to purchase a single piece of new, costly, specialized, commercially available instrument or an integrated instrumentation system. The BIG Program is limited to institutions that have not received S10 instrumentation funding of $500,001 or greater in any of the preceding 3 Federal fiscal years (FY). Use the following to determine applicable funding periods: for submission in CY 2026, consider S10 funding in FYs 2023-2025; for submission in CY 2027, consider S10 funding in FYs 2024-2026; for submission in CY 2028, consider S10 funding in FYs 2025-2027. The minimum award is $25,000. There is no maximum price limit for the instrument; however, the maximum award is $350,000. Instruments supported include, but are not limited to, basic cell sorters, confocal microscopes, ultramicrotomes, gel imagers, or computer systems.

Who can apply

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public and State controlled institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov Full announcement

Agency contact: National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

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