Limited Competition: Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) (P30 - Clinical Trial Not Allowed)

Federal funding opportunity PAR-27-055 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes May 25, 2029

Posted: June 18, 2026
Closes: May 25, 2029
Cost sharing: No
Instrument: Grant
Assistance listing: 93.859
Category: Health
Archives: July 24, 2029

Program funding history

Awards made under Assistance Listing 93.859 across FY2024–FY2026, from public federal spending records.

FY2024 obligated: $3B
FY2025 obligated: $3B
FY2026 (to date) obligated: $1.6B
Awards in window: 11,924

Top recipients: The Leland Stanford Junior University, Regents of the University of Michigan, Yale Univ, Trustees of the University of Pennsylvania, the, The Johns Hopkins University

Source: USAspending.gov · refreshed July 2026

Synopsis

The Institutional Development Award (IDeA) program supports biomedical research capacity building in states that have historically received low levels of NIH funding. The Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) Notice of Funding Opportunity (NOFO) supports the expansion and sustainability of biomedical research centers in IDeA-eligible institutions. These centers will focus on building research capacity in broad scientific areas of strategic importance for the institutions. The goal of COBRE-E is to expand research capacity by growing the institutional faculty base and supporting research projects and core facilities in the new area. The objective of COBRE-S is to sustain the infrastructure by continuing the growth of the faculty base and consolidating research cores. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.

Who can apply

County governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Small businesses
For profit organizations other than small businesses
Native American tribal governments (Federally recognized)
Special district governments
Public housing authorities/Indian housing authorities
City or township governments
Independent school districts
Public and State controlled institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
State governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Eligibility is restricted to institutions that meet all the following criteria:In an IDeA-eligible state, commonwealth, or jurisdiction, which are Alaska, Arkansas, Delaware, Hawaii, Idaho, Kansas, Kentucky, Louisiana, Maine, Mississippi, Montana, Nebraska, Nevada, New Hampshire, New Mexico, North Dakota, Oklahoma, Puerto Rico, Rhode Island, South Carolina, South Dakota, Vermont, West Virginia, and Wyoming; andAward doctoral degrees in health-related sciences or are independent biomedical research institutes/medical centers with ongoing biomedical research programs funded by the NIH or other federal agencies; andHold three or fewer active COBRE awards (except for COBRE Phase 3), including those in no-cost extension at the time of application submission. Applications will not be accepted from organizations that hold four or more active Phase 1, Phase 2, COBRE-D, COBRE-E, and COBRE-S awards, including those in no-cost extension.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · NIGMS_COBRE_E@mail.nih.gov · 301-402-2541

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