Archived

Drug Discovery For Nervous System Disorders (R01 Clinical Trials Not Allowed)

Federal funding opportunity PAR-22-031 from National Institutes of Health (Department of Health and Human Services).

Posted: November 29, 2021
Closed: January 7, 2025
Cost sharing: No
Instrument: Grant
Assistance listing: 93.279, 93.242, 93.866, 93.273
Category: Education, Health
Archives: February 12, 2025

Program funding history

Awards made under Assistance Listing 93.279 (one of 4 on this opportunity) across FY2025–FY2027, from public federal spending records.

FY2025 obligated: $1.5B
FY2026 obligated: $1.5B
FY2027 (to date) obligated: $0
Awards in window: 4,922

Top recipients: Yale Univ, The Johns Hopkins University, University of California, San Diego, University of Pittsburgh - of the Commonwealth System of Higher Education, Regents of the University of Michigan

Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →

This opportunity is archived. Applications are no longer accepted. Similar grants are listed below, and the free Tuesday digest carries the next ones like it.

Synopsis

Reissue of PAR-19-147 This Funding Opportunity Announcement (FOA) supports the discovery of novel compounds for the prevention and treatment of nervous system disorders. Through this FOA NIMH and NIA wish to stimulate research in: 1) Identification, design, synthesis, and preclinical testing of compounds of candidate therapeutics; 2) Initial hit-to-lead chemistry to improve activity of compounds against the target of interest; 3) Later stage lead optimization to improve efficacy and pharmacokinetics; and 4) Initial drug metabolism and pharmacokinetic (DMPK). Emphasis will be placed on projects that provide novel approaches for identifying potential therapeutic agents.

Who can apply

For profit organizations other than small businesses
State governments
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
City or township governments
Special district governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Small businesses
County governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

The official record

Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.

View on Grants.gov Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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Similar grants

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