Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
HEALTH AND HUMAN SERVICES, DEPARTMENT OF › NATIONAL INSTITUTES OF HEALTH › ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Responses are due 2029-03-05, 23:59 (UTC−05:00).
View on SAM.gov →Official listing
- Posted
- 2026-01-08
- Response deadline
- 2029-03-05, 23:59 (UTC−05:00)
- NAICS code
- 541715
- Product/service code
- AN13
- Place of performance
- USA
Description
This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSOs interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents: 1) Administrative & National Policy Requirements Document Updated the instructions and references within the Organizational Conflicts of Interest (OCI) Affirmations and Disclosure section. Updated questions, instructions, and content within the Research Security Disclosure section. Updated the instructions and intellectual property data assertions charts within the IP section. This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the Non-Commercial and Commercial tables were removed and replaced with the Background IP and Data Assertions table. Eliminated the Software Component Standards section. Updated the Human Subjects Research (HSR) table within the HSR section. Updated the Animal Subjects Research (ASR) table within the ASR section. Updated the questions and instructions within the Biosecurity section. 2) Cost Proposal Document (Word document) Updated the instructions within the Level of Effort and Labor Costs section. Added definitions for burdened labor rate and fully burdened labor rate to provide clarity for proposers when completing the document. Also added a statement to clarify that fully burdened labor rates are not used in the Cost Proposal Workbooks. Increased the threshold for proposers to provide supporting documentation with their proposal for planned materials and equipment purchases based on unit cost. The unit cost threshold was increased from $5,000 to $10,000. 3) Cost Proposal Workbooks (Excel spreadsheets) Updated instructions to clarify that ARPA-H will assume profit/fee is not applicable for proposals if proposers do not include profit/fee in the workbook. Updated the instructions for supporting documentation associated with planned materials and equipment purchases (based on the unit cost threshold increasing from $5,000 to $10,000). Completed administrative update to a tab
Primary contact
SEE DESCRIPTION SECTION · [email protected]
Every notice on this board links its official SAM.gov listing — verify details there before responding.
Run federal grants too?
Contract notices are free to browse and are not part of member fit-scoring, alerts, or the Tuesday digest — those cover grants. Members get every federal grant that opens fit-scored to their organization — with an alert when a real match posts.
See grants pricingGet the free Tuesday grants digest
One email a week: the biggest new federal grants and what’s closing soon — the same list for everyone. Contract notices stay on this free board. Unsubscribe any time.
Want contract alerts?
Fit-scored alerts cover grants today; this contracts board is free to browse. If alerts for contract notices would help your team, say so below — enough interest is what gets them built.