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NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

Federal funding opportunity RFA-RM-27-001 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes September 9, 2026

Posted
June 29, 2026
Closes
September 9, 2026
Award ceiling
$700,000
Award floor
$700,000
Program funding
$8,000,000
Expected awards
8
Cost sharing
No
Instrument
Grant
Assistance listing
93.310
Category
Health
Archives
November 8, 2026

Program funding history

Awards made under Assistance Listing 93.310 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$1.2B
FY2025 obligated
$1B
FY2026 (to date) obligated
$314.8M
Awards in window
4,776

Top recipients: Washington University, the, The Leland Stanford Junior University, The Johns Hopkins University, Yale Univ, New York University

Source: USAspending.gov · refreshed July 2026

Synopsis

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · PioneerAwards@mail.nih.gov · 301-402-2541

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