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NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional)

Federal funding opportunity RFA-RM-25-001 from National Institutes of Health (Department of Health and Human Services).

Posted
June 12, 2025
Closed
September 9, 2025
Award ceiling
$700,000
Cost sharing
No
Instrument
Grant
Assistance listing
93.310
Category
Health
Archives
October 15, 2025

Program funding history

Awards made under Assistance Listing 93.310 across FY2025–FY2027, from public federal spending records.

FY2025 obligated
$1B
FY2026 obligated
$993.8M
FY2027 (to date) obligated
$0
Awards in window
4,544

Top recipients: Washington University, the, The Leland Stanford Junior University, The Children's Hospital of Philadelphia, The Broad Institute, Inc, New York University

Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →

This opportunity is archived. Applications are no longer accepted. Similar grants are listed below, and the free Tuesday digest carries the next ones like it.

Synopsis

The NIH Directors Pioneer Award Program supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Directors Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

Who can apply

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

The official record

Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.

View on Grants.gov   Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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