Complement-ARIE New Approach Methodologies (NAMs) Technology Development Centers (UM1 Clinical Trial Optional)
- Posted
- December 10, 2024
- Closed
- March 18, 2025
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.310
- Category
- Health
- Archives
- April 17, 2025
Program funding history
Awards made under Assistance Listing 93.310 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1B
- FY2026 obligated
- $993.8M
- FY2027 (to date) obligated
- $0
- Awards in window
- 4,544
Top recipients: Washington University, the, The Leland Stanford Junior University, The Children's Hospital of Philadelphia, The Broad Institute, Inc, New York University
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The purpose of this Notice of Funding Opportunity (NOFO) is to establish Comprehensive NAMs Technology Development Centers to support NIH Common Funds Complement Animal Research In Experimentation (Complement-ARIE) program. The Complement-ARIE program will accelerate the development, standardization, validation, and use of human-based New Approach Methodologies (NAMs). Complement-ARIE will significantly advance understanding of human health and disease by providing a range of mature and/or validated and standardized biomedical research models. The goal of the Comprehensive NAMs Technology Development Centers is to stimulate the development of combinatorial NAMs to support scientific areas of need, with emphasis on increased biological complexity and throughput, innovative combinatorial approaches, and data sharing according to FAIR principles. Developing these NAMs will require multi-disciplinary expertise in disease research, personalized medicine, screening therapeutics for safety and efficacy, and regulatory science.
Who can apply
- Native American tribal governments (Federally recognized)
- City or township governments
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- State governments
- Special district governments
- Independent school districts
- For profit organizations other than small businesses
- County governments
- Small businesses
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
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