Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- September 14, 2026
- Closes
- See announcement
- Award ceiling
- $500,000
- Award floor
- $100,000
- Program funding
- $15,000,000
- Expected awards
- 20
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.113
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.113 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $444M
- FY2026 obligated
- $438.7M
- FY2027 (to date) obligated
- $0
- Awards in window
- 1,850
Top recipients: Icahn School of Medicine at Mount Sinai, Emory University, New York University, University of North Carolina at Chapel Hill, The Johns Hopkins University
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The purpose of this funding opportunity is to support mechanistic research to understand how exposure to metals and metal-containing compounds alters biological processes relevant to human health. Of particular interest are studies that elucidate the absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals, including mechanisms through which metals may alter immune homeostasis, cross the placental barrier, or gain access to and affect the central nervous system. Studies may employ experimental models, new approach methodologies, computational approaches, or leverage human biospecimens where these approaches are used to address defined mechanistic hypotheses.
Who can apply
- Special district governments
- Public and State controlled institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- City or township governments
- Public housing authorities/Indian housing authorities
- For profit organizations other than small businesses
- Independent school districts
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Native American tribal governments (Federally recognized)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Small businesses
- Private institutions of higher education
- State governments
- County governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
How to apply
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