Cooperative Program for Modeling Clinical Transplantation
Federal funding opportunity RFA-AI-27-017 from National Institutes of Health.
View forecast on Grants.gov →Forecasted — not yet open
- Posted
- April 9, 2026
- Closes
- See announcement
- Program funding
- $1,280,000
- Expected awards
- 3
- Cost sharing
- No
- Instrument
- Cooperative Agreement
- Assistance listing
- 93.855
- Category
- Health
Program funding history
Awards made under Assistance Listing 93.855 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $4.1B
- FY2025 obligated
- $4.2B
- FY2026 (to date) obligated
- $2.3B
- Awards in window
- 14,249
Top recipients: Fred Hutchinson Cancer Center, The Johns Hopkins University, Regents of the University of California, San Francisco, the, Washington University, the, Duke University
Source: USAspending.gov · refreshed July 2026
Synopsis
The National Institute of Allergy and Infectious Diseases (NIAID) will support its mission through the Cooperative Program for Modeling Clinical Transplantation. Advancements of new therapeutics and success in human solid organ transplantation will require innovative and clinically translatable in-vitro and in-vivo systems to model local and systemic immune responses. This program seeks applications including new approach methods (NAMs) and/or refined mouse models that together will promote translation of new therapies to clinical practice. Potential NAMs include immune-competent microphysiological systems, organoids, ex-vivo perfused human organs, precision-cut tissue slices, and computational systems biology models. Applicants must propose models designed to overcome known obstacles to clinical translation in existing NAMS and/or mouse models, reduce reliance on nonhuman primates, and demonstrate relevance to clinical outcomes. Emphasis on data sharing will facilitate reproducibility and establishment of standards and best practices to achieve the program goals. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- For profit organizations other than small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Native American tribal governments (Federally recognized)
- Special district governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Private institutions of higher education
- County governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Independent school districts
- Public and State controlled institutions of higher education
- Small businesses
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations
How to apply
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