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Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Federal funding opportunity PAR-27-022 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes July 1, 2028

Posted
June 25, 2026
Closes
July 1, 2028
Award ceiling
$5,000,000
Award floor
$300,000
Cost sharing
No
Instrument
Grant
Assistance listing
93.351, 93.855, 93.866, 93.867, 93.310, 93.859
Category
Health
Archives
August 30, 2028

Program funding history

Awards made under Assistance Listing 93.351 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$279M
FY2025 obligated
$281.4M
FY2026 (to date) obligated
$138.1M
Awards in window
1,100

Top recipients: University of California, Davis, Oregon Health & Science University, University of Washington, Emory University, Texas Biomedical Research Institute

Source: USAspending.gov · refreshed July 2026

Synopsis

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · odsig@mail.nih.gov · 301-402-2541

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