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Research Grants in Clinical Informatics (R01 Clinical Trial Optional)

Federal funding opportunity PAR-26-042 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes March 5, 2029

Posted
February 11, 2026
Closes
March 5, 2029
Award ceiling
$250,000
Program funding
$2,500,000
Expected awards
10
Cost sharing
No
Instrument
Grant
Assistance listing
93.879
Category
Health
Archives
May 4, 2029

Program funding history

Awards made under Assistance Listing 93.879 across FY2024–FY2026, from public federal spending records.

FY2024 obligated
$69.5M
FY2025 obligated
$78.9M
FY2026 (to date) obligated
$25.8M
Awards in window
400

Top recipients: The Leland Stanford Junior University, Yale Univ, University of Pittsburgh - of the Commonwealth System of Higher Education, Trustees of the University of Pennsylvania, the, University of Utah

Source: USAspending.gov · refreshed July 2026

Synopsis

The National Library of Medicine (NLM) seeks applications for innovative research in clinical informatics. The overarching goal of this forthcoming program is to catalyze the development and advancement of novel informatics methodologies that empower clinicians, patients, and the broader public to better understand, manage, and improve health and health care delivery. This NOFO will support research focused on the design, implementation, and evaluation of clinical informatics tools and methods that enable data-driven discovery, promote evidence-based decision-making, and support personalized and precision health care. Emphasis will be placed on domain-independent, scalable, and reusable/reproducible approaches for the discovery, analysis, organization, and management of health-related digital objects—including electronic health records (EHRs), clinical notes, imaging data, and patient-generated data. The aim is to transform raw and heterogeneous health data into actionable knowledge, to develop innovative tools, and to implement practical applications that can be generalized across multiple clinical settings and populations. Projects should demonstrate the potential to accelerate scientific insights, improve clinical workflows, and ultimately lead to improved health outcomes.

Who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source.

View on Grants.gov

Agency contact: National Institutes of Health · NLMProgram@nih.gov · 301-402-2541

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