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Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)

Federal funding opportunity PAR-25-158 from National Institutes of Health (Department of Health and Human Services).

Apply on Grants.gov →Application closes November 17, 2026

Posted: November 25, 2024
Closes: November 17, 2026
Cost sharing: No
Instrument: Grant
Assistance listing: 93.273
Category: Health
Archives: December 23, 2026

Program funding history

Awards made under Assistance Listing 93.273 across FY2024–FY2026, from public federal spending records.

FY2024 obligated: $445.1M
FY2025 obligated: $449M
FY2026 (to date) obligated: $278.7M
Awards in window: 2,284

Top recipients: Yale Univ, Trustees of Indiana University, University of North Carolina at Chapel Hill, University of California, San Diego, University of Washington

Source: USAspending.gov · refreshed August 2026

Synopsis

This Notice of Funding Opportunity (NOFO) focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenatal alcohol exposure and the incidence of FASD and that (2) interventions for FASD. These objectives will be accomplished with the Exploratory/Developmental Phased Award (R61/R33) mechanism, clinical trial optional. The R61 phase will support pilot studies or secondary data analysis for hypothesis development and feasibility, and research testing the hypotheses can be expanded in the R33 phase. The transition to the R33 phase will be determined by NIAAA program staff after evaluation of the achievement of specific milestones set for the R61 phase. Highest priority will be given to applications with clinical trials. Applicants interested in planning clinical trials or adding to current projects may also consider NOFO (TEMP-23832, the R34 option).

Who can apply

Public and State controlled institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
County governments
Small businesses
Native American tribal governments (Federally recognized)
City or township governments
Public housing authorities/Indian housing authorities
Special district governments
Private institutions of higher education
For profit organizations other than small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
State governments

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

How to apply

Applications go through the official government listing. Grants Radar links you straight to the source — applying is free.

View on Grants.gov Full announcement

Agency contact: National Institutes of Health · [email protected] · 301-402-2541

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