Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R21 Clinical Trial Optional)
Federal funding opportunity PAR-25-111 from National Institutes of Health (Department of Health and Human Services).
- Posted
- November 18, 2024
- Closes
- July 6, 2026
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.855, 93.279, 93.313, 93.865
- Archives
- August 5, 2026
Program funding history
Awards made under Assistance Listing 93.855 across FY2024–FY2026, from public federal spending records.
- FY2024 obligated
- $4.1B
- FY2025 obligated
- $4.2B
- FY2026 (to date) obligated
- $2.3B
- Awards in window
- 14,249
Top recipients: Fred Hutchinson Cancer Center, The Johns Hopkins University, Regents of the University of California, San Francisco, the, Washington University, the, Duke University
Source: USAspending.gov · refreshed July 2026
Synopsis
The purpose of this notice of funding opportunity (NOFO) is to support translational and clinical research to (1) advance precision medicine in pregnant women, lactating women, and children through the development of novel tools, models, and other technologies that could have a direct clinical or health impact; (2) enhance the understanding of the underlying mechanisms of drug action, including the role of pediatric ontogeny and the dynamic physiological changes that occur during pregnancy and lactation; and (3) discover and develop novel therapeutics or enhance the usage of existing drugs or drug repurposing for safer and more effective medications in pregnant and lactating women, neonates, and children. The overall goal is to improve safe and effective precision therapeutics for pregnant and lactating women, fetuses, neonates, and children, including those with disabilities.
Who can apply
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Independent school districts
- City or township governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Private institutions of higher education
- Public housing authorities/Indian housing authorities
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Small businesses
- For profit organizations other than small businesses
- State governments
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
How to apply
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