Precision Approaches in Radiation Synthetic Combinations (PAIRS, R21 Clinical Trial Optional)
- Posted
- June 14, 2022
- Closed
- May 23, 2025
- Award ceiling
- $275,000
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.395
- Archives
- June 22, 2025
Program funding history
Awards made under Assistance Listing 93.395 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1.3B
- FY2026 obligated
- $1.3B
- FY2027 (to date) obligated
- $0
- Awards in window
- 3,624
Top recipients: The Univeristy of Texas M.d. Anderson Cancer Center, Dana-farber Cancer Institute, Inc., Icahn School of Medicine at Mount Sinai, Fred Hutchinson Cancer Center, Sloan-kettering Institute for Cancer Research
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) will solicit R01 research projects that seek to investigate actionable synthetic vulnerabilities that can be conditionally paired with tumor responses to radiation therapy. The goal of the Precision Approaches in Radiation Synthetic Combinations (PAIRS) program is to develop radiation-synthetic combination strategies and facilitate their adoption into the precision medicine toolkit toward building new and effective anticancer treatments.
Who can apply
- Small businesses
- Independent school districts
- Public housing authorities/Indian housing authorities
- Special district governments
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- City or township governments
- Native American tribal governments (Federally recognized)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Public and State controlled institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
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