Precision Approaches in Radiation Synthetic Combinations (PAIRS, R01 Clinical Trial Optional)
- Posted
- June 14, 2022
- Closed
- May 23, 2025
- Cost sharing
- No
- Instrument
- Grant
- Assistance listing
- 93.395
- Archives
- June 22, 2025
Program funding history
Awards made under Assistance Listing 93.395 across FY2025–FY2027, from public federal spending records.
- FY2025 obligated
- $1.3B
- FY2026 obligated
- $1.3B
- FY2027 (to date) obligated
- $0
- Awards in window
- 3,624
Top recipients: The Univeristy of Texas M.d. Anderson Cancer Center, Dana-farber Cancer Institute, Inc., Icahn School of Medicine at Mount Sinai, Fred Hutchinson Cancer Center, Sloan-kettering Institute for Cancer Research
Source: USAspending.gov · refreshed October 2026 · Program page: awards, recipients and the opportunities under this listing →
Synopsis
The purpose of this Funding Opportunity Announcement (FOA) is to solicit R01 research projects that investigate actionable synthetic vulnerabilities that can be conditionally paired with tumor responses to radiation therapy. The goal the PAIRS program is to the development of radiation-synthetic combination strategies and facilitate their adoption into the precision medicine toolkit toward building new and effective anticancer treatments.
Who can apply
- For profit organizations other than small businesses
- Native American tribal organizations (other than Federally recognized tribal governments)
- Independent school districts
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Public housing authorities/Indian housing authorities
- Special district governments
- Small businesses
- Native American tribal governments (Federally recognized)
- State governments
- County governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- City or township governments
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
The official record
Grants.gov published the official terms and dates of this opportunity; this page keeps them as they were listed.
View on Grants.gov Full announcement
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